|
KMID : 0882420080740040445
|
|
Korean Journal of Medicine
2008 Volume.74 No. 4 p.445 ~ p.450
|
|
|
Air-leakage syndrome after allogeneic peripheral blood stem cell transplantation from unrelated donor
|
|
Kim Si-Hyun
Shin Joo-Young
Hwang Hyeon-Seok
Kim Dae-Joon
Kim Hee-Je
Min Woo-Sung
Kim Chun-Choo
|
|
|
Abstract
|
|
|
|
Bronchiolitis obliterans, a late, non-infectious pulmonary complication of bone marrow transplantation (BMT), is an obstructive airway disease associated with chronic graft-versus-host disease (cGVHD). We report a rare case of air-leakage syndrome including pneumothoraces, pneumomediastinum, and subcutaneous emphysema with bronchiolitis obliterans after allogeneic peripheral blood stem cell transplantation (PBSCT) from an unrelated donor. The pathogenesis of air-leakage syndrome is not fully understood, and its management has not yet been established. This patient was treated with high-concentration oxygen, tube thoracostomy, percutaneous drainage with a pigtail catheter to relieve the tension pneumomediastinum, and mechanical ventilatory support. The patient has now recovered and is being followed on an outpatient basis.
|
|
|
KEYWORD
|
|
|
Air-leakage syndrome, Bronchiolitis obliterans, Peripheral blood stem cell transplantation
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|